BiosyncX · The Governance Map
Two minutesFind your stage

The Governance Map

Seven stages between feeling fine and being governed.

You know your company's numbers to the decimal. Name your ApoB.

Ten questions or fewer. Two minutes. If you do not know a number, that is the answer.

Most executives run their health the way a founder runs a company before the first audit: on instinct, on how the quarter felt, and on the absence of bad news. The Governance Map is the audit. It places you on one of seven stages, decided by things you either have or do not have, and it names the single constraint of the stage you are in.

The seven stages of the Governance MapSeven plateaus rising from Unmeasured to Endowed. Each is opened by a count of things that exist, and the ground lightens as the climb goes up.0Unmeasured0 to 3 of 61Measured4 to 6 of 62Located6 ranked3Stabilized6 at target4Optimized6 at target, 5 of 5 precision5Governed4 reviews a year, 1 reader6Endowed2 registers, 2 documentsSTAGE

Every stage is opened by a count of things that exist. Nothing here is a feeling.

Find your stage

Ten questions or fewer.

The quiz asks what you know, and shows the targets inside the questions so you learn them while answering. Your stage appears on this page before anything is sent.

Where are you on the map?

Ten questions or fewer. If you do not know a number, that is the answer.

You are here

0

Unmeasured

You are here if
The constraint
Graduate by
The BiosyncX slot

Send me the Stage 0 guide.

The stage guide, the Six Numbers card, and the Leverage Ladder, within 48 hours. Then a short sequence written for your stage, and a reminder when your retest falls due.

Your guide arrives within 48 hours.

The Leverage Ladder is here if you would rather start now.

The seven stages

Seven stages. Find yours.

The map begins in the dark, where most executives over 40 are likely to be standing, and ends in the only stage that is about someone else. Each stage names where you are, the one thing in the way, and the test that moves you up.

You are here

Stage 0 · Passenger

Unmeasured

Your rolePassengerFewer than four of the six numbers exist, or they are older than a year. You feel fine.
Where the numbers are0 to 3 of 6known and dated within a year
The constraintRisk is unpricedThe key to Stage 0 is measurement.
Graduate byAll six numbers, dated within 90 days, in one place

You are now what the map calls a Passenger. Risk is being carried, and nobody is reading the instruments. That is why this stage is called Unmeasured.

The one lever

Get the six numbers. One laboratory visit, one tape measure, one home cuff, one fitness test. Spend nothing else until they exist.

Waits

  • The supplement order
  • The sauna
  • The longevity newsletter

Now

  • The cuff, seven days
  • The laboratory visit with ApoB on the form
  • The VO2 max test, booked

The human side

Stage 0 feels like nothing. That is the problem with it. The moment it stops feeling like nothing is usually the moment it becomes expensive.

Read the whole of Stage 0

When you hit Stage 0

Stage 0 is a company that has never been audited. Revenue is coming in, the founder feels good about the year, and nobody has opened the ledger. On the population evidence, most executives over 40 start here. The last full panel was for an insurance application. The blood pressure was read once, in a pharmacy, in 2023.

Feeling fine is the whole of the evidence, and feeling fine is exactly what a rising blood pressure and a rising ApoB feel like for twenty years. Stage 0 is where the preventable deaths on the Leverage Ladder are still unpriced, and it has the cheapest exit of any stage on this map.

Approximately half of adults with high blood pressure do not know they have it. NCD Risk Factor Collaboration 2021, Lancet.

Doing it right

  • Six results in one folder, each with a date
  • A home blood pressure cuff on the desk, used this week
  • A VO2 max test booked

Needs more work

  • ‘My doctor said everything was fine,’ and no numbers to show for it
  • A supplement order placed this month
  • A laboratory report from before the pandemic

The four strands at Stage 0

BodyNothing dated. The gate is the existence of six numbers.
MindSleep and alcohol are unrecorded. They wait.
PeopleNobody knows your numbers, including you.
PurposeUnexamined. That is allowed at Stage 0 and nowhere above it.

You are ready for Stage 1 when

  1. Six results in one folder
  2. Each result dated within 90 days
  3. Seven days of home readings on the cuff
  4. VO2 max measured by one method
  5. Grip strength measured
  6. You are ready to be Measured
Where BiosyncX fits

The Audit is the whole of Stage 0 bought in one visit. Every one of the six numbers, the precision layer, and a written report that ranks them. If the budget is the constraint, start with the cardiometabolic panel and add the rest later.

Ask about The Audit →

What comes next. Stage 1, where the numbers exist and the danger changes shape.

You are here

Stage 1 · Recordkeeper

Measured

Your roleRecordkeeperFour or more of the six numbers exist, dated within a year. Nobody has ranked them against optimal targets.
Where the numbers are4 to 6 of 6known, dated, and unranked
The constraintData without a decisionThe key to Stage 1 is ranking.
Graduate byName your single largest gap against an optimal target, in one sentence

You are now what the map calls a Recordkeeper. The file is complete and nobody has read it against a target. That is why this stage is called Measured.

The one lever

One physician reads the whole register against the optimal targets on the Six Numbers card, adds lipoprotein(a) once, and ranks the gaps by the Ladder, top tier first.

Waits

  • The third specialist
  • The repeat panel
  • The word normal

Now

  • The Six Numbers card beside the report
  • One physician reading all six
  • The two numbers nobody ordered: VO2 max and grip

The human side

Stage 1 feels like diligence. It is the stage where you have paid for the information and stopped short of the meaning, which was the part you were paying for.

Read the whole of Stage 1

When you hit Stage 1

Stage 1 is the audited company whose audit report sits in a drawer. The numbers exist. They arrived with the word normal beside most of them, and normal closed the file.

A laboratory reference range describes the central 95 percent of a group judged healthy when it was sampled. It describes what is common. The targets on this map describe what the trials aimed for. An ApoB of 110 mg/dL sits inside the reference range and is roughly double the map's target for someone who already has plaque, which is under 60. A systolic reading of 138 is a footnote on the report and a 25 percent difference in cardiovascular events in a randomised trial. Stage 1 is the most reassured stage on the map, and for that reason the stage where the wrong decision is easiest to make.

Fewer than half of US adults with hypertension have it controlled. Muntner 2020, JAMA (NHANES 2017 to 2018, 43.7 percent controlled).

Doing it right

  • You can state your largest gap in one sentence with a number in it
  • The lipid panel includes ApoB
  • One person has seen all six results together

Needs more work

  • ‘Everything came back normal’
  • Three doctors, no ranking
  • A cholesterol result without an ApoB beside it

The four strands at Stage 1

BodyMeasured, unranked. Usually missing VO2 max and grip, because nobody orders them.
MindReassured by the word normal. The reassurance is the risk.
PeopleSix specialists, six opinions, no priority.
PurposeStill unexamined.

You are ready for Stage 2 when

  1. Every result read against optimal
  2. ApoB is on the lipid panel
  3. One physician has seen all six together
  4. The gaps are ranked, top tier first
  5. The largest gap fits in one sentence with a number in it
  6. You are ready to be Located
Where BiosyncX fits

The Audit is the ranking you are missing. It reads every result you already hold against the optimal targets, closes the numbers nobody ordered, adds lipoprotein(a) once, and returns the one-sentence gap in writing. Bring recent results and they are credited against the panel.

Ask about The Audit →

What comes next. Stage 2, where the gap has a name and the calendar has not noticed.

You are here

Stage 2 · Owner

Located

Your roleOwnerYour results are ranked and you can name the largest gap. At least one of the six is off target, or nicotine is present.
Where the numbers are6 ranked1 to 5 at target, or nicotine present
The constraintKnowing without doingThe key to Stage 2 is one.
Graduate byNinety days on one Tier 1 lever, retested, and the number moved toward target

You are now what the map calls an Owner. The gap has a name and it sits on your desk with no date beside it. That is why this stage is called Located.

The one lever

One lever, the highest open one on the Ladder, executed to the written standard for 90 days, with the retest booked before the work starts. Medication is a lever where the number demands it, and a decision you take with the physician who owns the register.

Waits

  • The second and third protocol
  • The cold plunge
  • The argument about statins on principle

Now

  • One lever, the highest open on the Ladder
  • The standard written beside it
  • The retest, booked before the work starts

The human side

Stage 2 feels like control, because you know. Knowing is the least expensive form of doing nothing.

Read the whole of Stage 2

When you hit Stage 2

Stage 2 is the company that found the material weakness. It is on the risk register, it was discussed at the last meeting, and it has no owner, no budget, and no date.

This is where the longevity spending happens. The blood pressure is 145 over 92 and the cold plunge was delivered on Tuesday. The lever with the largest return is known, and it is the one that costs the most discomfort, so the money flows to the levers that cost nothing but money. The Ladder calls this majoring in the minors. The clinic calls it the pre-event visit.

Fewer than one in four US adults meets both the aerobic and the strength guideline. CDC National Health Interview Survey 2020.

Doing it right

  • The retest is booked
  • The number has moved since the last reading
  • The sauna is still in the catalogue

Needs more work

  • Three protocols running at once
  • A supplement stack for a blood pressure problem
  • The same number at the same level for a second year

The four strands at Stage 2

BodyOne Tier 1 lever at a time until all six are at target.
MindThe gap between knowing and doing is the whole constraint. A booked retest closes most of it. Sleep and alcohol enter here.
PeopleA physician who owns the lever, so the calendar cannot forget.
PurposeUnexamined, and rightly. Stage 2 is for one number.

You are ready for Stage 3 when

  1. One lever chosen, one
  2. The standard written beside it
  3. The retest booked in the calendar
  4. Ninety days executed without renegotiation
  5. The number moved toward target, and the next lever is open
  6. You are ready to be Stabilized
Where BiosyncX fits

The Program is the graduation test with a physician attached: one lever, one written standard, one retest date, and scheduled reviews so the calendar cannot forget. It begins the quarter you start and continues while there are levers open.

Ask about The Program →

What comes next. Stage 3, where the six numbers are at target and the risk you were never tested for is still there.

You are here

Stage 3 · Operator

Stabilized

Your roleOperatorAll six numbers at target. Nicotine zero. Fewer than four Tier 2 behaviours true most weeks, or fewer than three precision results on file. Lipoprotein(a) counts from Stage 1, and the calcium score from Stage 2.
Where the numbers are6 at targetprecision layer 0 to 2 of 5, or Tier 2 under 4 of 5
The constraintThe hidden liabilitiesThe key to Stage 3 is once.
Graduate byThe precision layer measured once, and four of the five Tier 2 items true most weeks

You are now what the map calls an Operator. The controls are clean and the balance sheet still has a page nobody has opened. That is why this stage is called Stabilized.

The one lever

The precision layer, once: lipoprotein(a), a calcium score, a hereditary cancer screen where your history calls for it, screening brought current, a micronutrient panel. Then Tier 2 of the Ladder, one item at a time.

Waits. The biohack of the month, The second cuff, The argument that the cholesterol is fine so the scan can wait.

The human side

Stage 3 feels finished. Tier 1 is closed and a family history is still open.

Read the whole of Stage 3

When you hit Stage 3

Stage 3 is the company with clean controls and an off-balance-sheet problem. Blood pressure, ApoB, glucose, fitness, and strength are at target. On the population evidence, the risk has fallen further than most people will ever take it.

What remains is the risk that never appears on the six numbers. A lipoprotein(a) that is inherited and untouched by diet. A coronary calcium score already above zero despite the lipid panel. A BRCA or Lynch variant that no lifestyle has any effect on. A micronutrient deficiency behind a normal blood count. Stage 3 is also where motivation fails, because the crisis is over and the numbers have become boring. Boring is the target.

Lipoprotein(a) is elevated in approximately one in five people and has been measured in well under 1 percent of them. Nordestgaard 2010, European Heart Journal; Bhatia 2023, JAHA (18,972 of 5,553,654 adults tested).

Doing it right

  • An Lp(a) result exists, once, for life
  • A calcium score exists
  • A fixed wake time on six of seven days

Needs more work

  • ‘My cholesterol is fine, so I do not need the scan’
  • Tier 1 numbers drifting while attention moves to biohacks
  • A family history of cancer and no genetic result

The four strands at Stage 3

BodySix at target. Now the inherited and structural risk: Lp(a), calcium, germline.
MindSleep regularity and alcohol under 100 g a week become gates, because they are counted.
PeopleOne standing weekly commitment with people who would notice your absence. This is a Tier 2 lever with mortality data behind it.
PurposeFirst question allowed: what is all of this for.

You are ready for Stage 4 when

  1. Lipoprotein(a) measured once, for life
  2. A calcium score exists, or your physician recorded why it is not yet needed
  3. Hereditary cancer screen done, and screening current
  4. Micronutrient panel on file
  5. Four of five Tier 2 items true most weeks
  6. You are ready to be Optimized
Where BiosyncX fits

The Modules are Stage 3 bought one system at a time, once the Audit has named which one is open. The Heart Audit covers the calcium score and lipoprotein(a). The Family Risk Audit covers the hereditary screen, with the conversation that has to come before it. The Cellular Audit covers the micronutrient panel.

Ask about The Modules →

What comes next. Stage 4, where everything has been measured once and nothing has been scheduled twice.

You are here

Stage 4 · Director

Optimized

Your roleDirectorTiers 1 and 2 closed. The precision layer known. No written register, or no review cycle with a date on it.
Where the numbers are6 at target, 5 of 5 precision0 dated reviews
The constraintDrift, no cadenceThe key to Stage 4 is cadence.
Graduate byA one-page register with a version number, a physician who reads it quarterly, and a mood and sleep record beside the six numbers

You are now what the map calls a Director. Everything was measured once and nothing has a next date. That is why this stage is called Optimized.

The one lever

Cadence. Blood pressure quarterly, the six numbers annually, VO2 max and grip every six months, one register document with an owner, and a physician who reads it every quarter.

Waits. The heroic month that redoes everything, The register kept in your head, The new wearable.

The human side

Stage 4 feels like maintenance, which is the word for the work nobody does.

Read the whole of Stage 4

When you hit Stage 4

Stage 4 is a well-run company without a board calendar. Everything was measured once and fixed once. Nothing is scheduled.

Blood pressure drifts a few points a year, and nobody notices a few points. The ApoB creeps back as the statin is quietly dropped. VO2 max falls approximately 3 to 6 percent a decade in the thirties and more than 20 percent a decade after 70, and faster than either when the interval session becomes a walk. The precision layer is dated the year you did it. Stage 4 is where the gains of Stages 2 and 3 are lost, slowly, in a way no single quarter reveals. It is also the first stage where the mind goes on the register, because the numbers that drift first are the ones nobody wrote down: sleep, alcohol, mood.

In adults over 65 prescribed a statin for prevention, approximately one in four was still taking it two years later. Jackevicius 2002, JAMA.

Doing it right

  • The next retest has a date
  • The register has a version number
  • A PHQ-9 sits on the register beside the ApoB, dated

Needs more work

  • ‘I did all of that in 2024’
  • The cuff is in a drawer
  • The statin stopped without a decision

The four strands at Stage 4

BodyHeld by cadence, or lost by drift. Every number has a next date.
MindMeasured for the first time: a mood and anxiety screen, fourteen nights of sleep, alcohol counted. Stress is priced through pressure, glucose, and sleep.
PeopleThe physician who owns the register. A quarterly hour that happens without you initiating it.
PurposeThe register asks what the cadence is for. Stage 5 answers.

The gates that enter at Stage 4

A mood and anxiety screen on the registerPHQ-9 and GAD-7, dated within a year, read by the physician who reads the rest. A screen is a number. A diagnosis is a conversation. The gate is that the screen exists and was read, never its score. A positive screen opens a Tier 2 lever the physician owns, and the register records that it was read and when. If the last question on the PHQ-9 scores anything above zero, that conversation happens the same day.
Fourteen nights of sleep on recordWake time, bedtime, wakes, alcohol. A study if three or more apnoea signs are present; the signs are listed in Governance SOP 4, and your physician orders the study.

You are ready for Stage 5 when

  1. A one-page register with a version number
  2. Every number has a next date
  3. A physician reads the register every quarter
  4. A mood and anxiety screen sits on it, dated
  5. Fourteen nights of sleep on record
  6. You are ready to be Governed
Where BiosyncX fits

The Program is the cadence. Your register, your retest dates, and a physician who reads the whole page every quarter and finds the drift before you feel it. This is the stage the Program was built for.

Ask about The Program →

What comes next. Stage 5, where the register is owned and the work changes from fixing to holding.

You are here

Stage 5 · Chair

Governed

Your roleChairA written register, reviewed by a physician every quarter, retested annually, with one reader who is not you. A written mandate exists.
Where the numbers are4 reviews a year, 1 reader1 mandate, retested annually
The constraintHolding the decadeThe key to Stage 5 is holding.
Graduate byFour quarterly reviews on record, every number current, and one person whose risk affects yours with a register of their own

You are now what the map calls a Chair. The register is owned, the cadence runs without you, and the question is what it is for. That is why this stage is called Governed.

The one lever

Hold the cadence, and write the mandate. One page: what the health is for, who it is for, and what you intend to be able to do at 70 that most people cannot.

Waits. The new protocol that replaces the review, The private register, The decade left to explain itself.

The human side

Stage 5 feels like nothing again. This time that is the evidence.

Read the whole of Stage 5

When you hit Stage 5

Stage 5 is governed. The register is reviewed quarterly, retested annually, and owned by a physician whose job is to find the drift before you feel it. Every lever the evidence ranks in Tiers 1 and 2 has been pulled and is being held.

The remaining work is the slow work: holding VO2 max against age, holding muscle through the sixties, keeping the ApoB at the level the regression trials aimed for. And the work that the numbers cannot do. Stage 5 is the first stage that asks what the decade is for, and requires the answer in writing. A mandate, one page, dated. It is the document a physician reads before the register, because it decides what the register is defending.

In 136,265 people, a strong sense of purpose tracked with approximately 17 percent lower all-cause mortality. Cohen 2016, Psychosomatic Medicine.

Doing it right

  • The quarterly review happened without you initiating it
  • Your spouse or partner can name your ApoB
  • The numbers are boring and current

Needs more work

  • The physician relationship lapsed
  • A new protocol replaced the review
  • A register nobody but you has read

The four strands at Stage 5

BodyHeld. The last decade is being defended now, thirty years early.
MindScreens retested annually. Sleep regularity held through travel.
PeopleA register with a reader. A partner who knows the numbers. Purpose in life and close ties each carry mortality data of the order of a Tier 2 lever.
PurposeThe mandate, in writing. What the decade is for.

The gates that enter at Stage 5

A register with a readerOne person who is not you knows your six numbers and the date of the next retest.
A written mandateOne page, dated. What the health is for, who it is for, and what you will do at 70 that most people cannot.

You are ready for Stage 6 when

  1. Four quarterly reviews on record
  2. Every number current at the annual retest
  3. One reader who is not you
  4. The mandate written and dated
  5. The review ran without you initiating it
  6. You are ready to be Endowed
Where BiosyncX fits

The Program continues, and at this stage its work changes from fixing to holding: the quarterly review, the annual retest, and the mandate kept beside the register.

Ask about The Program →

What comes next. Stage 6, the only stage on the map that is about someone else.

You are here

Stage 6 · Steward

Endowed

Your roleStewardStage 5 held for a full year, and at least one person whose risk affects yours holds a register of their own. Your paperwork is current.
Where the numbers are2 registers, 2 documentsone year held
The constraintKey person risk, yours and theirsThe key to Stage 6 is extension.
Graduate byThe next annual retest, yours and theirs, and the one after that. The map ends here

You are now what the map calls a Steward. What you hold is being held for other people, and it will keep funding what it was built for. That is why this stage is called Endowed.

The one lever

Extend the map. Run it across the people whose risk affects yours, starting with the one who would be hardest to replace. Offer them the Audit if they would never buy it for themselves.

Waits. Governing alone, Advice given instead of measurement, The paperwork left for a quieter year.

The human side

Stage 6 feels like giving something away. It is the first stage where the work leaves your body, and the first where the numbers of the people you love sit on your agenda.

Read the whole of Stage 6

When you hit Stage 6

Stage 6 is an endowment. Capital that outlives the person who built it and keeps funding the thing it was built for. Your register is current, reviewed, and read by someone else. The remaining risk on your balance sheet belongs to other people. A spouse at Stage 0. A co-founder who has never had a blood pressure read. A successor whose own numbers would end the company you are handing over.

This is the stage where the map stops being about you, and it is the calmest stage on it. Two documents live here that no other stage requires: an advance directive and a will, both dated within five years. They carry no mortality evidence of their own, and the map says so. They are the calmest documents on it, and the ones most people put off for a quieter year that never comes.

Approximately one in three US adults has an advance directive. Yadav 2017, Health Affairs.

Doing it right

  • The successor has a register with a date on it
  • Your partner's six numbers are on your quarterly agenda
  • The advance directive is dated within five years

Needs more work

  • The successor has never had a blood pressure read
  • A leadership team running at Stage 0 beneath a Chair at Stage 5
  • A will from before the second child

The four strands at Stage 6

BodyHeld, and now held for others. Your register is the template their registers follow. Their results stay theirs.
MindSteady. The paperwork has been done, which is the last of the unfinished business.
PeopleThe register has become plural. Key person risk is priced across the household and the board.
PurposeThe endowment. What you built keeps funding what it was built for after you have stopped working on it.

The gates that enter at Stage 6

A successor with a registerOne person whose risk affects yours has their own six numbers, dated, and their own reader.
The paperwork currentAn advance directive, or the nearest instrument your jurisdiction recognises, and a will, both drawn with your attorney and dated within five years. The calmest documents on the map. No mortality evidence, and one randomised trial on the family: wishes honoured in 86 percent against 30, with less stress and anxiety among relatives (Detering 2010, BMJ).

The graduation test, every year

  1. The next annual retest, yours
  2. The successor's first register, dated
  3. The paperwork dated within five years
  4. The team's stage distribution known
  5. The reviews continue without you
  6. There is no Stage 7
Where BiosyncX fits

The Audit, given. They book it themselves, they consent to every test, and their results go to them alone. If a whole leadership team is at Stage 0 beneath you, that is a separate conversation and it starts in the footer.

Ask about The Audit, for someone else →

What comes next. The Leverage Ladder, the free bonus: every lever on the map, ranked by effect and by evidence.

Working with us

Three plans. Your stage picks one.

Measure once, govern the levers, or buy a single system when the Audit has named it. Every stage on the map points at one of these three and never at a menu. Prices are set at booking, except the Cellular Audit, which is USD 900.

01

The Audit

Everything measured once, and ranked in writing.

Stages 0, 1 and 6

  • One visit. All six numbers, plus lipoprotein(a) and the precision layer your history calls for.
  • A written report that ranks every result against the optimal target, not the reference range.
  • The one-sentence gap, and the lever that closes it.

The front door. Recent results you already hold are credited against the panel.

Ask about the Audit →

02

The Program

A physician owns the register, the levers and the retests.

Stages 2, 4 and 5

  • One lever at a time, each with a written standard and a retest date booked before the work starts.
  • Pharmacology where the number demands it, decided with the physician who reads the whole register.
  • A quarterly review of a one-page register that carries a version number and an owner.

Monthly. It begins the quarter you start, and its work changes from fixing to holding as the numbers come to target.

Ask about the Program →

03

The Modules

One system at a time, once the Audit has named which.

Stage 3

  • The Heart Audit: the calcium score and lipoprotein(a).
  • The Family Risk Audit: the hereditary screen, with the conversation that comes before it.
  • The Cellular Audit, the Brain Audit, the Longevity Audit.

The Cellular Audit is USD 900 and credits in full against the Audit within 90 days. The rest are quoted at booking.

See the modules →

How the map places you

Decided by what exists. Held by cadence.

Your stage is decided by what exists.

A dated number. A ranked result. A booked retest. A written register. A named person. The quiz asks what exists. A number you cannot name has already placed you.

One constraint per stage. One lever per quarter.

Every stage names a single bottleneck and a single graduation test. You get permission to ignore everything else, which is the permission most executives are missing.

Stages are held, and stages are lost.

A business roadmap only goes up. Health drifts. A number that slips re-places you at the next retest, so the map is read again every quarter. The top of the map is a cadence, and the cadence has an owner.

The re-placement rule

  1. At every retest you occupy the highest stage whose gates you pass on that day.
  2. A number has three states. Current, inside its retest interval. Lapsed, up to twice that interval: you hold your stage and you cannot graduate. Unknown, beyond twice the interval or beyond a year, whichever comes first.
  3. The register moves you, up or down, and only the register. That is the point of having one.
  4. The quiz uses twelve months because you are placing yourself from memory. The register uses the retest interval, and the Audit places you by the register.

Four strands, seven stages

The body decides the first four stages.

The mind, the people around you, and the purpose decide the last three. Each strand enters the map only where the mortality evidence is strong enough to gate a stage. It enters as something that can be counted: a screen on the register, a person who reads it, a page that says what the decade is for.

See how the four strands shift across the stages
Four strands across seven stagesDot size shows how much each strand decides at each stage. The body decides the first four stages, the mind and the people the middle, purpose the top.0UNMEASURED1MEASURED2LOCATED3STABILIZED4OPTIMIZED5GOVERNED6ENDOWEDBODYMINDPEOPLEPURPOSE

Illustrative. The dots show where each strand enters the gates.

BodySix numbers, one gate, a precision layer

Blood pressure, ApoB, glucose and insulin, waist, fitness, strength. Then the inherited and structural risks the six cannot see.

MindSleep, alcohol, mood and stress, measured

A fixed wake time. Alcohol counted. A mood and anxiety screen on the register, dated like any other number.

PeopleWho would notice, who reads the register

One standing weekly commitment. A person who knows your six numbers. A physician who owns the register.

PurposeWhat the decade is for, and for whom

A written mandate. A successor with a register. The paperwork that outlives enthusiasm. These are the map's proxies for purpose and social integration, which carry the mortality data. The evidence sits behind the things, not the paperwork.

The gates

Six numbers decide the first four stages.

Each is cheap to obtain, each has a target that differs from the laboratory's reference range, and each carries evidence in the hundreds of thousands of patients. The grade beside each is the grade of that evidence, on the same scale the Leverage Ladder uses.

NumberTargetWhy this numberRetest

Home blood pressure, seven-day average

Under 130/80 on a validated home cuff. Your physician may set a lower target.

In trial data, every 10 mmHg off systolic pressure is associated with 13 percent lower all-cause mortality.

AQuarterly

ApoB

Under 80 mg/dL. Under 60 with a calcium score above zero, elevated Lp(a), or diabetes.

Every 1 mmol/L of LDL removed cuts major vascular events by 22 percent. ApoB counts the particles that do the damage.

AAnnually. Every six months on treatment.

HbA1c, with fasting insulin

HbA1c under 5.6 percent. Fasting insulin under 10 µIU/mL.

Diabetes nearly doubles all-cause mortality. Insulin often rises years before glucose does. HbA1c reads low with sickle cell trait and some anaemias, so your physician checks the variant once and adds a fasting glucose where it is called for.

AAnnually

Waist-to-height ratio

Under 0.50

Visceral fat is the earliest visible marker of the metabolic problem, and a tape measure finds it.

BQuarterly

VO2 max

Above the 50th percentile for age and sex. The top quartile is the aim.

The least fit fifth carries four to five times the mortality of the fittest. Moving from below average to above average is associated with approximately 30 percent lower risk.

BEvery six months

Grip strength

The top half for your age and sex. The EWGSOP2 sarcopenia floor is 27 kg for men and 16 kg for women, and regional norms differ.

Every 5 kg lost from grip strength tracks with 16 percent higher mortality.

BEvery six months

The gate. Smoking, and nicotine in any other form except replacement therapy used to stop, holds you at Stage 2 regardless of the six numbers. Nothing on this map compensates while it continues.

The rest of the gates: Tier 2, the precision layer, and the higher gates

Tier 2, counted most weeks

  • A fixed wake time within 30 minutes on six of seven days
  • Ultra-processed food under a fifth of what you eat
  • 8,000 steps on most days
  • Alcohol under 100 g a week
  • One standing weekly commitment with people who would notice your absence

The precision layer, once

  • Lipoprotein(a), once. Measured at Stage 1, because the ApoB target depends on it
  • Coronary artery calcium score, from Stage 2 where your physician needs it to set the ApoB target or choose the lever
  • Hereditary cancer genetic screen, where family history or your physician calls for it
  • Age-appropriate cancer screening, current
  • Micronutrient panel

The higher gates, in writing

  • A mood and anxiety screen on the registerEnters at Stage 4
  • Fourteen nights of sleep on recordEnters at Stage 4
  • A register with a readerEnters at Stage 5
  • A written mandateEnters at Stage 5
  • A successor with a registerEnters at Stage 6
  • The paperwork currentEnters at Stage 6

Sources for the six: Ettehad 2016 Lancet; Cholesterol Treatment Trialists 2010 Lancet; Emerging Risk Factors Collaboration 2011 NEJM; NICE 2022; Mandsager 2018 JAMA Network Open; Leong 2015 Lancet (PURE); EWGSOP2 2019. The full references sit at the end of the page and on the Ladder.

The free bonus

The map says where. The Ladder says what.

Twenty levers against mortality, ranked by how much each moves the number and by the quality of the evidence behind it, with a discard pile at the bottom. The rule that runs through it: never buy a Tier 4 solution to a Tier 1 problem.

Tier 0Measure firstThe full measurement
Tier 1Load-bearingCardiorespiratory fitness, Smoking, Blood pressure, Muscle strength and mass, ApoB and LDL, Metabolic health
Tier 2CompoundingSleep, Diet quality, Daily movement, Social connection, Alcohol, Depression, measured and treated
Tier 3MarginalAir quality, Sauna, Fish and omega-3, Stress load
Tier 4UnpricedEndocrine disruptors, Heavy metals, Pesticide residues, Supplements for longevity
DiscardNo data or harmDetox cleanses, Chelation for prevention, Nanobot detox, IV vitamin drips

Left off the map

What the map leaves out, and why.

A map is also a list of roads it does not show. Each of these is sold to executives every week, and each is missing here for a reason with a grade beside it.

  • CBiological age clocksEpigenetic and blood-based clocks predict mortality across populations and have no agreed target for one person. No trial shows that moving the clock moves the outcome. The Longevity Audit tracks it. It decides no stage.
  • CFull-body MRIFinds a confirmed cancer in approximately 1.6 percent of scans, with high rates of incidental findings and no survival data behind the screening. The map keeps age-appropriate cancer screening and the calcium score, which have it.
  • DContinuous glucose monitorsA useful teaching tool for a fortnight. In people without diabetes there is no outcome evidence, and HbA1c with fasting insulin carries the gate.
  • DNMN, resveratrol, and the longevity stackMouse data and mechanism. In adults not selected for deficiency, vitamin D, fish oil and a multivitamin each failed to lower mortality across approximately 69,000 trial participants. Test, then replace only what is low.
  • DCold plunges, red light, and the recovery cataloguePlausible mechanisms, small trials, no mortality data. They sit in Tier 3 and Tier 4 of the Ladder and they wait until Tiers 1 and 2 are closed.
  • BFeelings as a gateMood and stress matter enough to be on the register, so the map records them with a validated screen and a sleep log, and places you by what is on the record.

Evidence

What the gates rest on.

A: randomised trials or meta-analyses of them. B: large prospective cohorts, consistent across populations, with a dose-response. C: one cohort or cross-sectional. D: mechanism only. Nothing on the body gates a stage below grade B. The two documents at Stage 6 are governance, and the map says so.

The sources, row by row
  • ABlood pressureSPRINT 2015, NEJM (n=9,361). Ettehad 2016, Lancet (613,815 patients).
  • AApoB and LDLCholesterol Treatment Trialists 2010, Lancet (170,000). Ference 2012, JACC. Sniderman 2019, JAMA Cardiology.
  • AMetabolic healthEmerging Risk Factors Collaboration 2011, NEJM (820,900). SELECT 2023, NEJM.
  • BCardiorespiratory fitnessMandsager 2018, JAMA Network Open (122,007). Kokkinos 2022, JACC (750,302).
  • BGrip strengthLeong 2015, Lancet, PURE (139,691 across 17 countries).
  • ASmokingJha 2013, NEJM (202,248). Cessation trials: Cahill 2013, Cochrane (varenicline OR 2.88, nicotine replacement OR 1.84).
  • BSleep regularityWindred 2024, Sleep, UK Biobank (60,977).
  • BSocial connectionHolt-Lunstad 2010, PLoS Medicine (148 studies, 308,849; OR 1.50, and 1.91 for social integration). Religious service attendance: Li 2016, JAMA Internal Medicine (74,534 women).
  • BAlcoholWood 2018, Lancet (599,912 drinkers).
  • BPurpose in lifeCohen 2016, Psychosomatic Medicine (meta-analysis, 136,265). Alimujiang 2019, JAMA Network Open (6,985).
  • BMood and anxiety screeningDepression and mortality: Cuijpers 2014, American Journal of Psychiatry (1.8 million people, RR 1.64). PHQ-9: Kroenke 2001. GAD-7: Spitzer 2006. B for the association; no trial shows that screening lowers mortality.
  • BWaist-to-heightAshwell 2012, Obesity Reviews (31 studies, more than 300,000 adults); NICE 2022.
  • BVO2 max decline with ageFleg 2005, Circulation (Baltimore Longitudinal Study of Aging, 810 adults).
  • BAdvance directivesDetering 2010, BMJ (randomised, 309 inpatients: wishes honoured 86 percent against 30). Prevalence: Yadav 2017, Health Affairs. No mortality evidence; the outcome is the family's.
  • CCoronary calciumPolonsky 2010, JAMA, MESA (5,878 analysed). One cohort.
  • CStatin persistenceJackevicius 2002, JAMA: in adults over 65, two-year adherence 25.4 percent in primary prevention. One administrative cohort.
  • CFull-body MRI screeningMartins da Fonseca 2026, European Radiology: confirmed cancer in 1.57 percent of scans, no survival data.
  • BLipoprotein(a)Kamstrup 2009, JAMA (40,486; causal by Mendelian randomisation); Nordestgaard 2010, European Heart Journal (elevated is above the 80th percentile).

Questions

What you would ask in the room.

Is this medical advice?
No. The map is general information. The targets on it are optimal targets from the prevention literature, and they differ from diagnostic cut-offs on purpose. Your physician decides what your numbers mean for you. If you do not have one who reads the whole register, the map tells you what to ask for, and the Audit is one place to have it read.
I do not know most of these numbers. Where do I start?
At Stage 0, where most executives over 40 are likely to start, and which has the cheapest exit on the map. One laboratory visit, one tape measure, one home cuff, one fitness test. The Stage 0 guide names each.
Why is nicotine a gate and sleep is not?
Nothing on the map compensates for smoking while it continues. Smokers lose approximately a decade, and stopping before 40 removes approximately 90 percent of the excess risk. The map extends the gate to nicotine in every other form because the long-term data on vaping and pouches do not yet exist, and a gate on an unknown is cheaper than the alternative. Sleep regularity carries strong cohort data, and it is counted, so it is a Tier 2 item that gates Stage 4. The gate sits where the effect size, the evidence grade, and the map's ability to measure without diagnosing all sit. Depression is the clearest case: it carries a larger mortality signal than sleep regularity, so it sits in Tier 2 of the Ladder with a physician as the actor, and the map records that a screen was read rather than grading you on its score.
Why is biological age not one of the numbers?
Epigenetic clocks predict mortality across populations and have no agreed target for an individual, and no trial has shown that moving the clock moves the outcome. The Longevity Audit measures it as a tracking number. It decides no stage.
Can my stage go down?
Yes. That is the difference between this map and a business roadmap. A number that drifts re-places you at the next retest. Stage 4 exists because gains drift. In adults over 65 prescribed a statin for prevention, approximately one in four was still taking it two years later, and the cuff goes back in the drawer without anyone recording the date.
What about the mind, and purpose? Those cannot be measured.
They can be recorded. A mood and anxiety screen is a dated number. Fourteen nights of sleep is a record. A one-page mandate is a document. A successor with a register is a person you can name. The map places you by what exists, and it treats a written page the same way it treats a laboratory result.
Can my leadership team take this?
Yes. A company runs the map across its executive team and receives the stage distribution, the lecture, and a plan. Each executive takes part by their own choice, and taking part is never a condition of employment. The distribution is reported only when at least eight people took part, so no result can be traced to a person. No name, no number, and no stage reaches the employer. Each person receives their own guide directly.
What does the Audit cost?
The Audit is priced as a retained professional service, and the figure is shared at booking. The map, the stage guides, the Six Numbers card, the five Governance SOPs, and the Leverage Ladder are free.